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Md. Jamal Hossain

jamalhossain@sub.edu.bd

Assistant Professor & Assistant Proctor (SUB)

B. Pharm. & M. Pharm. (DU)

My name is Md. Jamal Hossain, and I am currently working as an assistant professor in the Department of Pharmacy, State University of Bangladesh, Dhaka, Bangladesh. Parallelly, I am holding the post of Assistant Proctor of the university. I have completed my M. Pharm with thesis (session: 2017-2018) from the Department of Pharmaceutical Chemistry, University of Dhaka, and B. Pharm (5 years professional; session: 2012-2013) from the Department of Pharmacy, University of Dhaka, Bangladesh. Before becoming a faculty member at SUB, I acquired experience as a research associate (RA) in the Chemical Biology and DNA Synthesis Lab from May 2020 to January 2021. My current research endeavors primarily revolve around diverse aspects of pharmacology and drug discovery & development. My primary focus is investigating various areas, including the chemical and biological analysis of natural compounds derived from natural sources through in vitro, in vivo, and in-silico approaches. Besides, I have been working on drug-drug interaction (synergistic and antagonistic effects), drug-biomolecular interactions, and organometallic chemistry since my M. Pharm. thesis program. Furthermore, I am keen on contributing to Public Health and Pharmacy Practice research, particularly in areas such as antimicrobial resistance and rational use of drugs. Apart from this, I am deeply interested in organic medicinal synthesis and evaluating potential biological activities to quest for new therapeutic possibilities. Amidst the COVID-19 pandemic, I was involved in various endeavors related to COVID-19 research. These included working on developing medications using lipids to combat COVID-19, repurposing existing drugs to fight SARS-CoV-2 infection, and conducting studies through questionnaires to tackle public health issues. Till August 2023, I have contributed to and authored over 100 peer-reviewed scientific publications with high-impact factors. Additionally, I have contributed to many journals as associate editor, peer reviewer, and review editor to enhance the publication and journal quality. Moreover, I am the initiator and principal instructor of a short course on “Molecular Docking: Basic to Advanced Applications” run by the Department of Pharmacy, SUB. My other important hobby is writing editorial columns/letters in national or international journals/newspapers on contemporary scientific issues. I am an editor of Pharma Tribune. At this stage, I aspire to be a Ph.D. candidate working on my passionate topics in a reputed research institution or laboratory, guided by a dedicated and inspiring professor.

Featured (Selected) Publications

Note: Asterisk (*) sign means corresponding authorship.

  1. Rashid PT, Hossain MJ*, Zahan MS, et al. Chemico-pharmacological and computational studies of Ophiorrhiza fasciculata D. Don and Psychotria silhetensis Hook. F. focusing cytotoxic, thrombolytic, anti-inflammatory, antioxidant, and anti-bacterial properties. Heliyon. 2023; 9(9); e20100. https://doi.org/10.1016/j.heliyon.2023.e20100
  2. Khatun MCS, Muhit MA, Hossain MJ, et al. Isolation of phytochemical constituents from Stevia rebaudiana (Bert.) and evaluation of their anticancer, antimicrobial and antioxidant properties via in vitro and in silico approaches. Heliyon 2021; 7(12): e08475. https://doi.org/10.1016/j.heliyon.2021.e08475 
  3. Jannat T, Hossain MJ*, El-Shehawi AM, et al. Chemical and pharmacological profiling of Wrightia coccinea (roxb. Ex hornem.) sims focusing antioxidant, cytotoxic, antidiarrheal, hypoglycemic, and analgesic properties. Molecules. 2022; 27(13): 4024. https://doi.org/10.3390/molecules27134024
  4. Farzana M, Hossain MJ*, El-Shehawi AM, et al. Phenolic constituents from Wendlandia tinctoria var. grandis (Roxb.) DC. Stem deciphering pharmacological potentials against oxidation, hyperglycemia, and diarrhea: phyto-pharmacological and computational approaches. Molecules. 2022; 27(18): 5957.  https://doi.org/10.3390/molecules27185957
  5. Sarwar S, Hossain MJ*, Irfan NM, et al. Renoprotection of selected antioxidant-rich foods (water spinach and red grape) and probiotics in gentamicin-induced nephrotoxicity and oxidative stress in rats. Life. 2022; 12(1): 60. https://doi.org/10.3390/life12010060
  6. Mukta M, Hossain MJ*, Akter M, et al. Cardioprotection of water spinach (Ipomoea aquatica), wood apple (Limonia acidissima) and linseed (Linum usitatissimum L.) on doxorubicin-induced cardiotoxicity and oxidative stress in rat model. Nutr Metab Insights 2023; 10.1177/11786388231212116
  7. Ripa FA, Hossain MJ*, Munira MS, et al. Phytochemical and pharmacological profiling of Trewia nudiflora Linn. leaf extract deciphers therapeutic potentials against thrombosis, arthritis, helminths, and insects. Open Chem. 2022; 20(1): 1304-12. https://doi.org/10.1515/chem-2022-0244
  8. Hossain MJ, Sultan MZ, Rashid MA, Kuddus MR. Does rabeprazole sodium alleviate the anti-diabetic activity of linagliptin? drug-drug interaction analysis by in vitro and in vivo methods. Drug Res. 2020; 70(11): 519-27. DOI: 10.1055/a-1233-3371
  9. Hossain MJ, Rashid MA, Sultan MZ. Transition metal chelation augments the half-life of secnidazole: molecular docking and fluorescence spectroscopic approaches. Drug Res. 2020; 70(12): 583-92. DOI: 10.1055/a-1252-2322
  10. Hossain MJ, Rahman SA. Repurposing therapeutic agents against SARS-CoV-2 infection: most promising and neoteric progress. Expert Rev. Anti-Infect. Ther. 2021; 19(8): 1009-27. https://doi.org/10.1080/14787210.2021.1864327
  11. Anjum N, Hossain MJ, Aktar F, et al. Potential in vitro and in vivo bioactivities of Schleichera oleosa (lour.) oken: A traditionally important medicinal plant of Bangladesh. Res J. Pharm. Technol. 2022;15(1):113-21. DOI: 10.52711/0974-360X.2022.00019
  12. Rahman MM, Soma MA, Sultana N, Hossain MJ*. Exploring therapeutic potential of Woodfordia fruticosa (L.) Kurz leaf and bark focusing on antioxidant, antithrombotic, antimicrobial, anti-inflammatory, analgesic, and antidiarrheal properties. Health Sci. Rep. 2023, 6 (10): e1654. https://doi.org/10.1002/hsr2.1654
  13. Ripa FA, Hossain MJ*, Nesa M, et al. Phytochemical and pharmacological profiling of Heritiera fomes Buch. Ham. deciphered thrombolytic, antiarthritic, anthelmintic, and insecticidal potentialities via in vitro approach. Evidence-Based Complement. Alternat. Med. 2022; 2022: 2594127. https://doi.org/10.1155/2022/2594127
  14. Hoque N, Khan ZR, Rashid PT, Begum MN, Sharmin S, Hossain MJ et al. Antimicrobial, antioxidant, and cytotoxic properties of endophytic fungi isolated from Thysanolaena maxima Roxb., Dracaena spicata Roxb. and Aglaonema hookerianum Schott. BMC Complement Med Ther. 2023; 23(1): 347. https://doi.org/10.1186/s12906-023-04185-4
  15. Das R, Rauf A, Mitra S, Emran TB, Hossain MJ, et al. Therapeutic potential of marine macrolides: An overview from 1990 to 2022. Chemico-Biological Interactions. 2022; 365:110072. https://doi.org/10.1016/j.cbi.2022.110072    
  16. Mitra S, Rauf A, Sutradhar H, Sadaf S, Hossain MJ, et al. Potential candidates from marine and terrestrial resources targeting mitochondrial inhibition: Insights from the molecular approach. Comp Biochem Physiol C. 2023; 264: 109509. https://doi.org/10.1016/j.cbpc.2022.109509
  17. Hossain MJ*, Ahmmed F, Rahman SMA, et al. Impact of online education on fear of academic delay and psychological distress among university students following one year of COVID-19 outbreak in Bangladesh. Heliyon 2021; 7(6). e07388. https://doi.org/10.1016/j.heliyon.2021.e07388
  18. Hossain MJ*, Jabin N, Ahmmed F, et al. Irrational use of antibiotics and factors associated with antibiotic resistance: Findings from a cross‐sectional study in Bangladesh. Health Sci. Rep. 2023; 6(8): e1465. https://doi.org/10.1002/hsr2.1465
  19. Hossain MJ*, Ahmmed F, Khan MR, et al. Impact of prolonged covid-19 lockdown on body mass index, eating habits, and physical activity of university students in Bangladesh: a web-based cross-sectional study. Front. Nutr. 2022; 9. https://doi.org/10.3389/fnut.2022.873105
  20. Hossain MJ*, Ahmmed F, Sarker MMR, et al. Factors associated with underprivileged e-Learning, session jam phobia, and the subsequent mental distress among students following the extended university closure in Bangladesh. Front. Public Health. 2022; 9: 2303. https://doi.org/10.3389/fpubh.2021.807474
  21. Brishty SR, Hossain MJ, Khandaker MU, Faruque MRI, Osman H, Rahman SMA. A Comprehensive Account on Recent Progress in Pharmacological Activities of Benzimidazole Derivatives. Front Pharmacol. 2021; 12: 762807. doi: 10.3389/fphar.2021.762807  
  22. Das R, Mitra S, Tareq AM, Emran TB, Hossain MJ, Alqahtani AM, Alghazwani Y, Dhama K, Simal-Gandara J. Medicinal plants used against hepatic disorders in Bangladesh: A comprehensive review. J Ethnopharmacol. 2022; 282: 114588. doi: 10.1016/j.jep.2021.114588.
  23. Ghosh B, Rahman MM, Saha T, Hossain MJ, Alam S, Al-Aman DAA, Kayser MS, Islam MS, Islam MK, Singh A, Ahmed T. Drinking Water Sources along the Banks of Buriganga River of Bangladesh are Polluted and Possess Serious Health Risks: A Comprehensive In Vivo Analysis. J Environ Public Health. 2023; 2023: 3369163. doi: 10.1155/2023/3369163.
  24. Anjum J, …, Hossain MJ, Aljohani ASM, Abdulmonem WA, Alsharif KF, Alzahrani KJ, Khan H. A renewed concept on the MAPK signaling pathway in cancers: Polyphenols as a choice of therapeutics. Pharmacol Res. 2022; 184: 106398. doi: 10.1016/j.phrs.2022.106398.
  25. Sultana A, Hossain MJ*, Kuddus MR, Rashid MA, Zahan MS, Mitra S, Roy A, Alam S, Sarker MMR, Naina Mohamed I. Ethnobotanical Uses, Phytochemistry, Toxicology, and Pharmacological Properties of Euphorbia neriifolia Linn. against Infectious Diseases: A Comprehensive Review. Molecules. 2022 ; 27(14): 4374. doi: 10.3390/molecules27144374.
  26. Mitra S, …, Hossain MJ, Emran TB. Prospective multifunctional roles and pharmacological potential of dietary flavonoid narirutin. Biomed Pharmacother. 2022; 150: 112932. doi: 10.1016/j.biopha.2022.112932.
  27. Hossain MJ, Rabaan AA, Mutair AA, Alhumaid S, Emran TB, Saikumar G, Mitra S, Dhama K. Strategies to tackle SARS-CoV-2 Mu, a newly classified variant of interest likely to resist currently available COVID-19 vaccines. Hum Vaccin Immunother. 2022; 18(1): 2027197. doi: 10.1080/21645515.2022.2027197.
  28. Bari MS, Hossain MJ*, Ahmmed F, Sarker MMR, Khandokar L, Chaithy AP, Aziz F, Mitra S, Emran TB, Islam MS, Islam MR, Mohamed IN. Knowledge, Perception, and Willingness towards Immunization among Bangladeshi Population during COVID-19 Vaccine Rolling Period. Vaccines (Basel). 2021 Dec 7;9(12):1449. doi: 10.3390/vaccines9121449.
  29. Tallei TE,…,Hossain MJ, Emran TB. Fruit Bromelain-Derived Peptide Potentially Restrains the Attachment of SARS-CoV-2 Variants to hACE2: A Pharmacoinformatics Approach. Molecules. 2022 Jan 1;27(1):260. doi: 10.3390/molecules27010260.
  30. Alam S, …, Hossain MJ, Kim JK, Kim B, Hasib MS, Zihad SMNK, Haque MR, Mohamed IN, Rashid MA. Antidiabetic Potential of Commonly Available Fruit Plants in Bangladesh: Updates on Prospective Phytochemicals and Their Reported MoAs. Molecules. 2022 Dec 8;27(24):8709. doi: 10.3390/molecules27248709.
  31. Akash S, …, Hossain MJ, Rashid MA, Kumer A, Ghosh A, León-Figueroa DA, Barboza JJ, Padhi BK, Sah R. Modified coptisine derivatives as an inhibitor against pathogenic Rhizomucor miehei, Mycolicibacterium smegmatis (Black Fungus), Monkeypox, and Marburg virus by molecular docking and molecular dynamics simulation-based drug design approach. Front Pharmacol. 2023 Apr 19;14:1140494. doi: 10.3389/fphar.2023.1140494.
  32. Amee KN,…., Hossain MJ, Hasan R, Sarker MM. Phytochemical Profiling and Evaluation for Anti-oxidant, Thrombolytic, and Antimicrobial Activities of Moringa oleifera Lam Leaves Extracts. Biomedical & Pharmacology Journal. 2023 Jun;16(2):1027-36. DOI : https://dx.doi.org/10.13005/bpj/2684
  33. Hossain MJ*, Ahmmed F, Khandokar L, Rahman SMA, Hridoy A, Ripa FA, Emran TB, Islam MR, Mitra S, Alam M. Status of psychological health of students following the extended university closure in Bangladesh: Results from a web-based cross-sectional study. PLOS Glob Public Health. 2022 Mar 31;2(3):e0000315. doi: 10.1371/journal.pgph.0000315.
  34. El-Mageed HA, …, Hossain MJ, Capasso R, Emran TB. In silico evaluation of different flavonoids from medicinal plants for their potency against SARS-CoV-2. Biologics. 2021; 1(3): 416-34. DOI: https://doi.org/10.3390/biologics1030024
  35. Uddin TM,…, Hossain MJ, Koirala N. Antibiotic resistance in microbes: History, mechanisms, therapeutic strategies and future prospects. J Infect Public Health. 2021; 14(12): 1750-1766. doi: 10.1016/j.jiph.2021.10.020.

Notable conference presentation/talk

  1. Hossain MJ. In-vitro, in-vivo and in-silico profiling of Foeniculum vulgare (fennel seed) provided pharmacological potentialities against oxidation, inflammation, pain and diarrhea. ICPS-2023 (May 11-12, 2023), Dhaka, Bangladesh.
  2. Hossain MJ. Antimicrobial resistance: a global concern and its tackling strategy through antimicrobial natural products. Biannual Faculty Development Program (FDP). State University of Bangladesh (Dec 17, 2022). 
  1. ‘Researcher Award’ for having the highest number of publications in 2022-2023.
  2. ‘Best Poster Award’ (1st Prize among SUB Participants) at the International Conference on Pharmaceutical Sciences held on May 11-12, 2023, at the permanent campus of the State University of Bangladesh, Dhaka, Bangladesh. 
  3. Listed in top contributor list in Scopus Database 2022 of Bangladeshi scientist. 
  4. Awarded with NST Fellowship, 2019-20 from Ministry of Science and Technology, Bangladesh.



News

*** Admission going on for Fall 2024 *** LLB Admission test will be held on May 11, 2024 *** LLB Admission form last submission date May 09, 2024 *** Congratulations! to all the newly enrolled advocates from the State University of Bangladesh ***
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